When standard antidepressants fall short, it is easy to lose hope of real relief. Spravato in Tupelo offers a groundbreaking solution for adults facing treatment-resistant depression by pairing the rapid action of esketamine with compassionate, physician-led care. Delivered as a nasal spray under supervision, this therapy has brought measurable relief to patients who had nearly given up on getting better.
By combining research insights with close patient monitoring, our mental health professionals at Right Track Medical Group can help turn your clinical data into personal progress. Best of all, you can receive this treatment without any major disruption to your regular schedule. Read on to understand what you can expect with this type of treatment.
Spravato® (esketamine) is an FDA-approved nasal spray treatment for adults living with treatment-resistant depression (TRD) or major depressive disorder (MDD) accompanied by suicidal thoughts or actions. Unlike standard antidepressants that can take weeks to work, Spravato acts quickly on brain pathways involved in mood regulation, offering new hope to those who have not found relief with other therapies.
At Right Track Medical Group, Spravato is administered in a safe, supportive environment under the direct supervision of our healthcare team in Tupelo. Each session is designed with your comfort in mind, so you can focus on healing while we carefully monitor your progress and adjust your treatment plan as needed.
Determining whether esketamine therapy in Tupelo may be suited to you starts with a comprehensive psychiatric evaluation. During this assessment, we will review your medication history, diagnosis, and physical health. To be considered eligible, you must have tried at least two antidepressants—at adequate doses— without experiencing lasting relief.
We typically offer SPRAVATO to:
To ensure your safety, we consider lab results and blood-pressure baselines to identify conditions, such as uncontrolled hypertension, that need optimization before dosing. For women of childbearing age, we will advise you on pregnancy testing and contraception, as Spravato therapy is not recommended during pregnancy.
We offer substance-use screening to protect you from harmful interactions and provide the support you may need. In addition, our care team will explain REMS program requirements so you can make an informed decision.
For the first month, your Spravato sessions will take place twice a week at our Tupelo clinic, tapering to once a week and then once every two weeks as stability improves. Our staff works to ensure a calming environment with dimmed lights and reclining chairs—and noise-canceling headphones are available on request to help reduce sensory overstimulation.
After we administer the esketamine, you will stay for observation while our clinicians track your vital signs, mood, and any side effects—adjusting your care plan in real time. You can bring a trusted friend or family member for emotional support. As driving is restricted until the morning after your treatment, you will need someone to drive you home after each visit.
Between sessions, you can report progress or ask questions via secure patient-portal messaging, keeping the treatment loop tight and responsive. This structured yet flexible approach helps you move forward with minimal disruption to your schedule.
Clinical trials and real-world data show that about 70 percent of patients experience a minimum 50 percent drop in depressive symptoms after four to eight weeks of SPRAVATO therapy. Remission rates are close to 50 percent—a remarkable figure for individuals who found other methods ineffective.
Your chance of success rises when you combine esketamine with weekly psychotherapy, maintain consistent sleep, and avoid alcohol or illicit substances that could reduce the effectiveness of the treatment.
At our Tupelo clinic, many Spravato clients report early improvements in motivation, energy, and cognitive clarity, which then translate into stronger relationships and improved work performance.
Spravato in Tupelo offers hope to residents who have battled depression through countless medications without finding lasting respite. By combining an advanced scientific mechanism with robust safety protocols and whole-person support, our care providers at Right Track Medical Group can guide you toward real change. Call us today and get yourself on the right track to long-term wellness.