If you have struggled to find relief from depression through conventional medications, Spravato treatment may offer a promising alternative. At Right Track Medical Group, we offer medically supervised Spravato treatment in Starkville as part of our comprehensive, patient-centered approach to depression care.
Call us today to schedule your consultation and learn more about how our
mental health professionals may be able to help you.
What Is Spravato?
Spravato® is a prescription nasal spray formulation of esketamine, which is an enantiomer—a mirror image—of ketamine. Unlike traditional antidepressants that primarily influence serotonin or norepinephrine, esketamine acts on the glutamate system in the brain, supporting new neural connections and enhancing synaptic plasticity.
It was first approved by the FDA in 2019 for treatment-resistant depression, specifically for adults who have not found relief from at least two adequate trials of oral antidepressants. Because Spravato may cause sedation, dissociation, or other side effects, it is only available under a Risk Evaluation and Mitigation Strategy program, and all treatment must occur in certified clinics under medical supervision, such as at our Right Track Medical Group clinic in Starkville.
Who Is a Candidate for Spravato?
If you live in Starkville, you might be a candidate for Spravato treatment if:
- You have tried at least two different antidepressants with inadequate responses
- You are experiencing moderate to severe depression that continues despite standard treatments
- You have depression with suicidal thoughts
- You are willing to participate in close monitoring before, during, and after each treatment session
Spravato is not appropriate for everyone. We will evaluate safety, medical history, and potential risks before recommending it.
What To Expect During Treatment
Let us explain how the Spravato treatment process at Right Track Medical Group in Starkville works:
Pretreatment Evaluation and Baseline Assessment
We will review your depression history, current medications, physical health, and any contraindications
Dose Administration
You will administer the nasal spray yourself in our clinic under close supervision
Posttreatment Monitoring
After administration, you will stay in the clinic for two hours—or longer if necessary—so our staff can monitor your vital signs, mental status, and any side effects
Benefits and Limitations
As with any other medication or treatment in Starkville, there are benefits and limitations to receiving Spravato treatment.
Potential Benefits
With Spravato's rapid onset, you could experience meaningful reductions in your depressive symptoms within hours or days of your treatment. If you have not responded to conventional therapies, Spravato offers the hope of relief from your treatment-resistant symptoms, and the expanded FDA approval means you may now receive Spravato without needing to take an oral antidepressant concurrently.
Limitations and Risks
Side effects—especially early in treatment—may include dissociation, sedation, increased blood pressure, nausea, dizziness, or perceptual disturbances. The long-term safety and effectiveness beyond several months have not been fully established. Not everyone responds to Spravato, and its continued use should be evaluated regularly.
How We Use Spravato
At
Right Track Medical Group in Starkville, we integrate Spravato into a holistic treatment program. Here is how we approach treatment:
Comprehensive Assessment
We thoroughly assess your psychiatric history, medical status, and past treatment responses.
Personalized Treatment Plan
You may also receive
psychotherapy,
medication management, lifestyle support, or other therapies.
Close Collaboration and Monitoring
During each treatment, we monitor you closely and ask you for ongoing feedback.
Outcome Evaluation
We continuously assess your symptom improvement, functional gains, and any side effects.
Contact Our Starkville Clinic if You Think Spravato Treatment May Be Right for You
If you have treatment-resistant depression, Spravato may offer you an alternative treatment option. However, because it requires medical oversight and is not a universal solution, it is important that you meet with a qualified provider who can evaluate your suitability and help you assess the benefits and risks.
If you are ready to explore Spravato treatment in Starkville as part of your depression treatment program,
reach out to Right Track Medical Group today. We will help you understand whether it is right for you and guide you through the next steps.